Download GGGA data

*It was updated on May 18, 2021, and older versions is available here.
Release the single-cell sequencing data from CGGA Network (6,148 cells from 73 regions of 13 glioma patients) (April 15, 2021)

DataSet ID: Spatiotemporal transcriptome data
Data type: mRNA sequencing
Platform: Illumina HiSeq
Total number of samples: Longitudinal samples: 141; Spatial samples: 67
If you use this part of the data (or method included in it), please consider to cite:

Feng, J., Zhao, Z., Wei, Y., Bao, Z., et al. Temporal and Spatial Stability of the EM/PM Molecular Subtypes in Adult Diffuse Glioma. (To be submitted).
Further information and requests for resources should be directed to the Lead Contact, Tao Jiang or Xiaolong Fan (taojiang1964@163.com or xfan@bnu.edu.cn)

DataSet ID: Spatiotemporal WES data
Data type: Whole-exome sequencing
Platform: Agilent SureSelect kit v5.4 & Illumina HiSeq 4,000
Total number of samples: Longitudinal samples: 10; Spatial samples: 67
If you use this part of the data (or method included in it), please consider to cite:

1. Yang, C., Tan, Y., Li, S., Zhou, J., et al. (2019). Genomic landscapes by multiregion sequencing combined with circulation tumor DNA detection contribute to molecular diagnosis in glioblastomas. Aging 11, 11224-11243
2. Feng, J., Zhao, Z., Wei, Y., Bao, Z., et al. Temporal and Spatial Stability of the EM/PM Molecular Subtypes in Adult Diffuse Glioma. (To be submitted).
Further information and requests for resources should be directed to the Lead Contact, Tao Jiang or Xiaolong Fan (taojiang1964@163.com or xfan@bnu.edu.cn)

DataSet ID: Image-genomic data
Data type: Image-genomic data
Platform: MRI
Total number of samples: 274
If you use this part of the data (or method included in it), please consider to cite:

Li, Y., Liang, Y., Sun, Z., et al. Radiogenomic analysis of PTEN mutation in glioblastoma using preoperative multi-parametric magnetic resonance imaging. Neuroradiology. 2019 Nov;61(11):1229-1237.
Further information and requests for resources should be directed to the Lead Contact, Tao Jiang (taojiang1964@163.com)

DataSet ID: scRNA-seq
Data type: Single-cell sequencing
Platform: STRT-seq
Total 6,148 cells, involving in 73 regions from 13 patients.
If you use this part of the data (or method included in it), please consider to cite:

Yu, Kai., Hu, Yuqiong., Wu, Fan., et al. Surveying brain tumor heterogeneity by single-cell RNA-sequencing of multi-sector biopsies (2020). National Science Review 7(8):1306–1318
Further information and requests for resources should be directed to the Lead Contact, Tao Jiang (taojiang1964@163.com)



DataSet ID: mRNAseq_325
Data type: mRNA sequencing
Platform: Illumina HiSeq 2000 or 2500
Total number of samples: 325
If you use this part of the data (or method included in it), please consider to cite:

1. Bao, Z.S., Chen, H.M., Yang, M.Y., Zhang, C.B., Yu, K., Ye, W.L., Hu, B.Q., Yan, W., Zhang, W., Akers, J., et al. (2014). RNA-seq of 272 gliomas revealed a novel, recurrent PTPRZ1-MET fusion transcript in secondary glioblastomas. Genome research 24, 1765-1773
2. Zhao, Z., Meng, F., Wang, W., Wang, Z., Zhang, C., and Jiang, T. (2017). Comprehensive RNA-seq transcriptomic profiling in the malignant progression of gliomas. Scientific data 4, 170024
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DataSet ID: methyl_159
Data type: DNA methylation microarray
Platform: Illumina Infinium HumanMethylation27 Bead-Chips
Total number of samples: 159
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DataSet ID: microRNA_198
Data type: microRNA microarray
Platform: human v2.0 miRNA Expression BeadChip (Illumina)
Total number of samples: 198
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DataSet ID: mRNA sequencing (non-glioma as control)
Data type: Illumina HiSeq
Total number of samples: 20
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*Browse the 'About' section for details of data processing



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