circRNA basic information
circBase ID: hsa_circ_0000247
Name: hsa_circ_MCU
Synonym: -
Host Gene: MCU
Genomic location(hg19): chr10:74474868-74475660:+
Genomic location(hg38): chr10:72715110-72715902:+
Subcellular localization: exosome
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005184
MONDO name: pancreatic ductal adenocarcinoma
Disease details: pancreatic ductal adenocarcinoma / PDAC
Disease DO ID:
 3498, 3587
Disease MeSH ID:
 D021441
Disease NCIt ID:
 C9120
Disease ICD11 ID:
 581089833
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

serum exosomes; tumor tissues; normal tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
Q
M
Validation methods:

Microarray; RNase R Treatment; RT-qPCR; Clinical Sample Validation
Clinical significance:

-
Description:

hsa_circ_0000247 is up-regulated in PDAC and was validated by qRT-PCR; the study did not experimentally establish a specific mechanism for this circRNA in PDAC.
Confidence score:

0.4773
Other information
Title:

Differential expression and bioinformatics analysis of exosome circRNAs in pancreatic ductal adenocarcinoma.

Journal: Translational oncology
Published: 2023
PubMed ID: 37182508
Study type:

combined biological and clinical study
Data availability: GSE79634; GSE163031; GSE15471
Code availability: -