circRNA basic information
circBase ID: -
Name: gga_circ_FOXP1
Synonym: NC_006099.4: 15993284|16006290
Host Gene: FOXP1
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0000827
MONDO name: salmonellosis
Disease details: Salmonella enterica serovar Enteritidis (SE) inoculation
Disease DO ID:
 0060859
Disease MeSH ID:
 D012480
Disease NCIt ID:
 C157974
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Chicken
Species details: Gallus gallus
Tissue specimen:

cecum
Cell lines:

-
In vivo animal model:

other disease animal model
circRNA-disease information
Expression pattern:
DS
Associated gene: FOXP1
Associated microRNA: -
Biological function: May regulate response to SE inoculation via FOXP1 and miRNAs.
Molecular mechanism: Potential miRNA sponge/ceRNA mechanism (predicted).
Biological pathway or process:

ceRNA regulation (other)
Detected method:
S
Validation methods:

RNA-seq; Bioinformatics Analysis; In Vivo Animal Model
Clinical significance:

-
Description:

This FOXP1-derived circRNA is significantly altered after SE inoculation, with an expression direction opposite to another FOXP1 circRNA. The paper proposes it may modulate SE-response through FOXP1/miRNA-related regulation, but details are not experimentally resolved.
Confidence score:

0.31
Other information
Title:

Cecal CircRNAs Are Associated With the Response to Salmonella Enterica Serovar Enteritidis Inoculation in the Chicken.

Journal: Frontiers in immunology
Published: 2019
PubMed ID: 31214170
Study type:

biological research
Data availability: SRP158084
Code availability: -