circRNA basic information
circBase ID: -
Name: hsa_circ_AKT3
Synonym: circRNA AKT3
Host Gene: AKT3
Genomic location(hg19): chr1:243545509-243695716:-
Genomic location(hg38): chr1:243382207-243532414:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0858950
MONDO name: traumatic brain injury
Disease details: Traumatic brain injury / TBI
Disease DO ID:
 0081292
Disease MeSH ID:
 -
Disease NCIt ID:
 -
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

TBI tissues; adjacent brain contusion tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: FTO
Associated microRNA: -
Biological function: unknown
Molecular mechanism: not specified
Biological pathway or process:

not specified
Detected method:
Q
S
Validation methods:

RNase R Treatment; RNA-seq; RT-qPCR; Clinical Sample Validation
Clinical significance:

-
Description:

AKT3 circRNA is significantly down-regulated in human TBI brain tissue and this change was validated by RT-qPCR. The study does not provide specific mechanistic or functional validation for AKT3 circRNA beyond differential expression.
Confidence score:

0.4773
Other information
Title:

Expression characteristics of circular RNA in human traumatic brain injury.

Journal: Frontiers in neurology
Published: 2022
PubMed ID: 36712438
Study type:

combined biological and clinical study
Data availability: BankIt2634779: OP794505-OP79462
Code availability: -