circRNA basic information
circBase ID: hsa_circ_0002557
Name: hsa_circ_FARP1
Synonym: hsa_circ_0002557_CBC1 / circ_0002557
Host Gene: FARP1
Genomic location(hg19): chr13:98865473-98865667:+
Genomic location(hg38): chr13:98213219-98213413:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0008383
MONDO name: rheumatoid arthritis
Disease details: rheumatoid arthritis / RA
Disease DO ID:
 7148
Disease MeSH ID:
 D001172
Disease NCIt ID:
 C2884
Disease ICD11 ID:
 576319925
Disease OMIM ID:
 180300
Species: Human
Species details: Homo sapiens
Tissue specimen:

peripheral blood mononuclear cells / PBMCs
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: unknown
Molecular mechanism: not specified
Biological pathway or process:

not specified
Detected method:
Q
M
Validation methods:

Microarray; RT-qPCR; Clinical Sample Validation; Bioinformatics Analysis
Clinical significance:

Expression level correlates negatively with inflammation/laboratory indices (CRP, RF).
Description:

hsa_circ_0002557 is down-regulated in RA PBMCs and validated by RT-qPCR. Its expression is negatively correlated with CRP and RF in RA patients.
Confidence score:

0.4032
Other information
Title:

Profiling of differentially expressed circRNAs and functional prediction in peripheral blood mononuclear cells from patients with rheumatoid arthritis.

Journal: Annals of medicine
Published: 2023
PubMed ID: 36661308
Study type:

combined biological and clinical study
Data availability: The datasets used and analysed during this study are available from the corresponding author on reasonable request.
Code availability: -