circRNA basic information
circBase ID: hsa_circ_0007396
Name: -
Synonym: hsa_circRNA_102476
Host Gene: -
Genomic location(hg19): chr19:17270204-17273932:+
Genomic location(hg38): chr19:17159394-17163122:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0001056
MONDO name: gastric cancer
Disease details: gastric cancer / GC
Disease DO ID:
 10534
Disease MeSH ID:
 -
Disease NCIt ID:
 C9331
Disease ICD11 ID:
 1397617262
Disease OMIM ID:
 613659
Species: Human
Species details: Homo sapiens
Tissue specimen:

normal gastric tissue; GC tumor tissue
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: CHD4
Associated microRNA: miR-767-3p
Biological function: associated with GC progression, proliferation and carcinogenesis
Molecular mechanism: putative ceRNA axis involving miR-767-3p and downstream target CHD4 (bioinformatics-predicted)
Biological pathway or process:

proliferation (other); ceRNA regulation (other)
Detected method:
M
Validation methods:

Microarray; Bioinformatics Analysis
Clinical significance:

-
Description:

This study identified hsa_circ_0007396 as a down-regulated circRNA in gastric cancer using GEO datasets. A predicted regulatory axis hsa_circ_0007396/miR-767-3p/CHD4 was proposed as being associated with GC proliferation and carcinogenesis based on bioinformatics analyses.
Confidence score:

0.1768
Other information
Title:

The hsa_circ_0007396-miR-767-3p-CHD4 axis is involved in the progression and carcinogenesis of gastric cancer.

Journal: Journal of gastrointestinal oncology
Published: 2022
PubMed ID: 36636050
Study type:

bioinformatics study
Data availability: GSE83521; GSE89143
Code availability: -