circRNA basic information
circBase ID: hsa_circ_0000914
Name: hsa_circ_FKBP8
Synonym: -
Host Gene: FKBP8
Genomic location(hg19): chr19:18648410-18649246:-
Genomic location(hg38): chr19:18537600-18538436:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0013792
MONDO name: intracerebral hemorrhage
Disease details: intracerebral hemorrhage / ICH
Disease DO ID:
 -
Disease MeSH ID:
 D002543
Disease NCIt ID:
 -
Disease ICD11 ID:
 873092535
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

peripheral blood
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: Independent predictor of ICH occurrence (logistic regression).
Molecular mechanism: not specified
Biological pathway or process:

not specified
Detected method:
Q
S
Validation methods:

RNA-seq; RT-qPCR; Clinical Sample Validation; Bioinformatics Analysis
Clinical significance:

Higher hsa_circ_0000914 is associated with lower odds of ICH occurrence (adjusted OR 0.160).
Description:

hsa_circ_0000914 is down-regulated in ICH peripheral blood and was confirmed by RT-qPCR. Higher expression is associated with reduced odds of ICH occurrence in adjusted logistic regression.
Confidence score:

0.4032
Other information
Title:

Machine learning-based identification of the novel circRNAs circERBB2 and circCHST12 as potential biomarkers of intracerebral hemorrhage.

Journal: Frontiers in neuroscience
Published: 2022
PubMed ID: 36523430
Study type:

combined biological and clinical study
Data availability: GSA-Human: HRA001807
Code availability: -