circRNA basic information
circBase ID: hsa_circ_0008016
Name: hsa_circ_FGFR1
Synonym: -
Host Gene: FGFR1
Genomic location(hg19): chr8:38287199-38287466:-
Genomic location(hg38): chr8:38429681-38429948:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0006337
MONDO name: ovarian endometriosis
Disease details: ovarian endometriosis
Disease DO ID:
 11432
Disease MeSH ID:
 -
Disease NCIt ID:
 C27628
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

ectopic endometrium (ecEM); eutopic endometrium (euEM); cyst walls of ovarian endometriomas
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: might play a role in the development and progression of endometriosis
Molecular mechanism: ceRNA (miRNA sponge) mechanism (predicted, not specified for this circRNA)
Biological pathway or process:

ceRNA regulation (other)
Detected method:
Q
S
Validation methods:

RNA-seq; RT-qPCR; Clinical Sample Validation; Bioinformatics Analysis
Clinical significance:

-
Description:

hsa_circ_0008016 (from host gene FGFR1) is significantly overexpressed in ectopic endometrium in ovarian endometriosis. It is included in the study’s predicted ceRNA network, but no specific miRNA/mRNA axis is experimentally validated for this circRNA.
Confidence score:

0.4032
Other information
Title:

Circular RNA expression profiles and bioinformatics analysis in ovarian endometriosis.

Journal: Molecular genetics & genomic medicine
Published: 2019
PubMed ID: 31144476
Study type:

combined biological and clinical study
Data availability: -
Code availability: -