circRNA basic information
circBase ID: hsa_circ_0009022
Name: -
Synonym: -
Host Gene: -
Genomic location(hg19): chr18:9583114-9595100:-
Genomic location(hg38): chr18:9583116-9595102:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005575
MONDO name: colorectal cancer
Disease details: colorectal cancer / CRC
Disease DO ID:
 5672, 9256
Disease MeSH ID:
 -
Disease NCIt ID:
 C4978
Disease ICD11 ID:
 -
Disease OMIM ID:
 114500
Species: Human
Species details: Homo sapiens
Tissue specimen:

CRC tissues; adjacent normal tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DS
Associated gene: coexpressed mRNAs
Associated microRNA: -
Biological function: Potentially important role in regulating differential gene expression in CRC through coexpression with mRNAs and predicted miRNA binding.
Molecular mechanism: Predicted circRNA-mRNA coexpression and circRNA-miRNA binding network.
Biological pathway or process:

ceRNA regulation (other); other pathway/process (other)
Detected method:
S
Validation methods:

RNA-seq; Bioinformatics Analysis
Clinical significance:

Potential candidate diagnostic biomarker and therapeutic target as part of the differentially expressed circRNA set.
Description:

hsa_circ_0009022 was identified as a hub circRNA in CRC based on RNA-seq-derived coexpression networks. It showed high correlation with coexpressed mRNAs and predicted high miRNA-binding affinity, suggesting a possible regulatory role in CRC gene expression.
Confidence score:

0.1768
Other information
Title:

Analysis of differentially expressed circular RNAs for the identification of a coexpression RNA network and signature in colorectal cancer.

Journal: Journal of cellular biochemistry
Published: 2019
PubMed ID: 30320923
Study type:

bioinformatics study
Data availability: Supporting Information Data1
Code availability: -