circRNA basic information
circBase ID: -
Name: hsa_circ_WDR37
Synonym: -
Host Gene: WDR37
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0015924
MONDO name: pulmonary arterial hypertension
Disease details: pulmonary arterial hypertension
Disease DO ID:
 -
Disease MeSH ID:
 D000081029
Disease NCIt ID:
 -
Disease ICD11 ID:
 1931148955
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

whole-blood samples
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: unknown
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
Q
M
Validation methods:

Microarray; RT-qPCR; Clinical Sample Validation; ROC Analysis
Clinical significance:

Evaluated by ROC curve (AUC 0.8225) for predicting potential association with PAH.
Description:

hsa_circWDR37_016 is significantly up-regulated in PAH-COPD patient whole blood and shows good diagnostic performance by ROC analysis (AUC 0.8225). The study did not report mechanistic or functional validation for this circRNA.
Confidence score:

0.4679
Other information
Title:

hsa_circNFXL1_009 modulates apoptosis, proliferation, migration, and potassium channel activation in pulmonary hypertension.

Journal: Molecular therapy. Nucleic acids
Published: 2021
PubMed ID: 33614247
Study type:

clinical study
Data availability: Supplemental Information can be found online at https://doi.org/10.1016/j.omtn.2020.09.029.
Code availability: -