circRNA basic information
circBase ID: hsa_circ_0082333
Name: -
Synonym: -
Host Gene: -
Genomic location(hg19): chr7:129756284-129762042:+
Genomic location(hg38): chr7:130116444-130122202:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0007256
MONDO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma / HCC
Disease DO ID:
 684, 686
Disease MeSH ID:
 D006528
Disease NCIt ID:
 C3099
Disease ICD11 ID:
 1294035808
Disease OMIM ID:
 114550
Species: Human
Species details: Homo sapiens
Tissue specimen:

HCC tissues; noncancerous liver tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DS
Associated gene: CDC6, GINS1, MCM4, MCM6, MCM7
Associated microRNA: hsa-miR-10a-5p, hsa-miR-150-5p, hsa-miR-214-5p, hsa-miR-23b-3p, hsa-miR-26a-5p, hsa-miR-486-5p
Biological function: Potential ceRNA component that may promote HCC progression (bioinformatic inference).
Molecular mechanism: ceRNA hypothesis (circRNA-miRNA-mRNA network).
Biological pathway or process:

cell cycle (promotes); DNA replication (promotes); ceRNA regulation (other)
Detected method:
M
Validation methods:

Microarray; Bioinformatics Analysis; ROC Analysis
Clinical significance:

Has diagnostic value in HCC (ROC AUC>0.7).
Description:

hsa_circ_0082333 was identified as a differentially expressed circRNA in HCC via microarray dataset integration and included in a predicted circRNA-miRNA-mRNA ceRNA network. It was reported to have diagnostic value by ROC analysis, with no experimental validation reported.
Confidence score:

0.348
Other information
Title:

Identification of lncRNA/circRNA-miRNA-mRNA ceRNA Network as Biomarkers for Hepatocellular Carcinoma.

Journal: Frontiers in genetics
Published: 2022
PubMed ID: 35386284
Study type:

bioinformatics study
Data availability: GSE97332; GSE164803; GSE45267; GSE101685; TCGA
Code availability: -