circRNA basic information
circBase ID: -
Name: -
Synonym: hsa_circ_00001666
Host Gene: -
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005575
MONDO name: colorectal cancer
Disease details: colorectal cancer
Disease DO ID:
 5672, 9256
Disease MeSH ID:
 -
Disease NCIt ID:
 C4978
Disease ICD11 ID:
 -
Disease OMIM ID:
 114500
Species: Human
Species details: Homo sapiens
Tissue specimen:

CRC tissues; normal tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: CXCR5
Associated microRNA: has-mir-1229
Biological function: May play an important role in the pathogenesis of CRC.
Molecular mechanism: circRNA-associated competing endogenous RNA (ceRNA) mechanism via a circRNA/miRNA/mRNA axis.
Biological pathway or process:

ceRNA regulation (other)
Detected method:
S
Validation methods:

RNA-seq; Bioinformatics Analysis
Clinical significance:

-
Description:

This study suggests that hsa_circ_00001666 is down-regulated in colorectal cancer and may participate in CRC pathogenesis via a ceRNA axis involving has-mir-1229 and CXCR5. The conclusion is based on public GEO/TCGA datasets and interaction predictions, without experimental validation.
Confidence score:

0.1768
Other information
Title:

Circular RNA-Associated Competing Endogenous RNA Network and Prognostic Nomogram for Patients With Colorectal Cancer.

Journal: Frontiers in oncology
Published: 2019
PubMed ID: 31781492
Study type:

bioinformatics study
Data availability: GSE126095; TCGA (https://portal.gdc.cancer.gov/)
Code availability: -