circRNA basic information
circBase ID: hsa_circ_0006459
Name: hsa_circ_GNAQ
Synonym: circ_0006459
Host Gene: hsa-miR-940
 
 
 
Disease basic information
DO ID:
 6713
DO name: cerebrovascular disease
Disease details: ischemic stroke
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: FOXJ2
Associated microRNA: hsa-miR-940
Biological function: Circ_0006459 depletion assuaged OGD-induced inhibition in cell proliferation and promotion in cell apoptosis and inflammation in HBMECs.
Molecular mechanism: circ_0006459/hsa-miR-940/FOXJ2 axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

Depletion of circ_0006459 protected human brain microvascular endothelial cells from oxygen-glucose deprivation-induced damage through miR-940/FOXJ2 pathway, providing a promising therapeutic target for ischemic stroke.
Other information
Title:

Depletion of circ_0006459 protects human brain microvascular endothelial cells from oxygen-glucose deprivation-induced damage through the miR-940/FOXJ2 pathway.

Journal: Transpl Immunol
Published: 2023/1/8
PubMed ID: 36608833