circRNA basic information
circBase ID: hsa_circ_0064644
Name: hsa_circ_RBMS3
Synonym: -
Host Gene: RBMS3
Genomic location(hg19): chr3:29910348-29941246:+
Genomic location(hg38): chr3:29868857-29899755:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0008315
MONDO name: prostate cancer
Disease details: prostate cancer
Disease DO ID:
 10283
Disease MeSH ID:
 D011471
Disease NCIt ID:
 C7378
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

-
Cell lines:

22Rv1; LNCaP; VCaP; DU145; PC-3; BPH-1; PWR1; RWPE-1; PWR-1E; RWPE-1
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: RBMS3
Associated microRNA: miR-15a
Biological function: -
Molecular mechanism: Predicted miRNA binding (miR-15a) suggesting a potential ceRNA-like role; no experimental validation reported.
Biological pathway or process:

ceRNA regulation (other)
Detected method:
M
Validation methods:

Microarray; Bioinformatics Analysis
Clinical significance:

-
Description:

hsa_circ_0064644 is down-regulated in malignant versus benign/normal prostate cell lines. Bioinformatic analyses link it to the host gene RBMS3 and predict interaction with miR-15a, suggesting a potential miRNA-related regulatory role in prostate cancer.
Confidence score:

0.1768
Other information
Title:

Differential CircRNA Expression Signatures May Serve as Potential Novel Biomarkers in Prostate Cancer.

Journal: Frontiers in cell and developmental biology
Published: 2021
PubMed ID: 33718350
Study type:

bioinformatics study
Data availability: The raw data supporting the conclusions of this article will be made available by the authors, without undue reservation.; https://www.frontiersin.org/articles/10.3389/fcell.2021.605686/full#supplementary-material
Code availability: -