circRNA basic information
circBase ID: hsa_circ_0081143
Name: -
Synonym: -
Host Gene: -
Genomic location(hg19): chr7:94044537-94055169:+
Genomic location(hg38): chr7:94415225-94425857:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0001056
MONDO name: gastric cancer
Disease details: gastric cancer
Disease DO ID:
 10534
Disease MeSH ID:
 -
Disease NCIt ID:
 C9331
Disease ICD11 ID:
 1397617262
Disease OMIM ID:
 613659
Species: Human
Species details: Homo sapiens
Tissue specimen:

GC tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: SERPINE1
Associated microRNA: miR-145
Biological function: might contribute to GC progression and prognosis
Molecular mechanism: Predicted ceRNA mechanism: sponging miR-145 to regulate SERPINE1
Biological pathway or process:

ceRNA regulation (other)
Detected method:
M
Validation methods:

Microarray; Bioinformatics Analysis
Clinical significance:

indicating the prognostic role of hsa_circ_0081143 for GC patients
Description:

hsa_circ_0081143 is computationally identified as up-regulated in gastric cancer tissues and is predicted to act as a ceRNA sponge for miR-145, thereby regulating SERPINE1. The study suggests it may have prognostic relevance in GC via the SERPINE1 link.
Confidence score:

0.1768
Other information
Title:

A Robust Circular RNA-Associated Three-Gene Prognostic Signature for Patients with Gastric Cancer.

Journal: BioMed research international
Published: 2021
PubMed ID: 33969120
Study type:

bioinformatics study
Data availability: GEO; TCGA
Code availability: -