circRNA basic information
circBase ID: hsa_circ_0123115
Name: hsa_circ_FGF12
Synonym: circ_0123115
Host Gene: FGF12
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0002974
MONDO name: cervical cancer
Disease details: cervical cancer / CC
Disease DO ID:
 4362
Disease MeSH ID:
 -
Disease NCIt ID:
 C9311
Disease ICD11 ID:
 1256072522
Disease OMIM ID:
 603956
Species: Human
Species details: Homo sapiens
Tissue specimen:

formalin-fixed paraffin-embedded cervical tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: Potential biomarker for early detection and monitoring of cervical cancer; may contribute to malignant transformation.
Molecular mechanism: not specified
Biological pathway or process:

not specified
Detected method:
S
Validation methods:

circRNA-seq; Clinical Sample Validation; Bioinformatics Analysis
Clinical significance:

Promising biomarker for early detection and monitoring of cervical cancer.
Description:

circ_0123115 (FGF12-associated) is strongly upregulated in cancerous versus benign cervical tissues in this FFPE cohort and is proposed as a candidate biomarker for early detection/monitoring of cervical cancer. The study suggests it may relate to malignant transformation, but no functional mechanism was experimentally validated.
Confidence score:

0.3991
Other information
Title:

Novel circRNA signatures in cervical cancer: implications for early detection and screening.

Journal: Biomarkers in medicine
Published: 2026
PubMed ID: 41715885
Study type:

combined biological and clinical study
Data availability: GSE102686; GSE107472
Code availability: -