circRNA basic information
circBase ID: hsa_circ_0108457
Name: hsa_circ_SETBP1
Synonym: circSETBP1
Host Gene: SETBP1
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005575
MONDO name: colorectal cancer
Disease details: colorectal cancer / CRC
Disease DO ID:
 5672, 9256
Disease MeSH ID:
 -
Disease NCIt ID:
 C4978
Disease ICD11 ID:
 -
Disease OMIM ID:
 114500
Species: Human
Species details: Homo sapiens
Tissue specimen:

CRC tissues; tumor-adjacent normal control (NC) tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Biological pathway or process:

ceRNA regulation (other)
Detected method:
Q
S
Validation methods:

RNA-seq; RT-qPCR; Back-Splice Junction PCR / divergent primers PCR; Bioinformatics Analysis; Clinical Sample Validation
Clinical significance:

-
Description:

The study reports hsa_circ_0108457 (circSETBP1) as down-regulated in colorectal cancer tissues versus adjacent normal tissues and confirms its back-splicing by computational validation, with expression trend validated by RT-qPCR. No specific miRNA or downstream target mechanism is established for this circRNA in the paper.
Confidence score:

0.5135
Other information
Title:

Comprehensive analysis of m6A circRNAs identified in colorectal cancer by MeRIP sequencing.

Journal: Frontiers in oncology
Published: 2022
PubMed ID: 36059637
Study type:

combined biological and clinical study
Data availability: -
Code availability: -