circRNA basic information
circBase ID: -
Name: ebv_circ_RPMS1
Synonym: circRPMS1_E4_E2
Host Gene: RPMS1
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0001056
MONDO name: gastric cancer
Disease details: stomach cancer
Disease DO ID:
 10534
Disease MeSH ID:
 -
Disease NCIt ID:
 C9331
Disease ICD11 ID:
 1397617262
Disease OMIM ID:
 613659
Species: Virus
Species details: Human gammaherpesvirus 4 / Epstein-Barr virus
Tissue specimen:

stomach cancer biopsies; normal adjacent tissue; tumor tissue
Cell lines:

Akata; Mutu I; Sav I; Mutu III; IB4; JY
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UN
Associated gene: -
Associated microRNA: -
Biological function: unknown
Molecular mechanism: unknown
Biological pathway or process:

not specified
Detected method:
Q
S
Validation methods:

RNA-seq; RNase R Treatment; divergent primers PCR; Back-Splice Junction PCR; Sanger Sequencing; Clinical Sample Validation; RT-PCR
Clinical significance:

Detected in EBV positive stomach cancer biopsies (2/2 patients).
Description:

circRPMS1_E4_E2 is an EBV RPMS1-locus circRNA expressed across latency types and detectable in EBV-positive stomach cancer biopsies. The study validates its circularity by RNase R resistance and junction sequencing but does not report a specific mechanism or subcellular localization for this circRNA.
Confidence score:

0.606
Other information
Title:

The Epstein Barr virus circRNAome.

Journal: PLoS pathogens
Published: 2018
PubMed ID: 30080890
Study type:

combined biological and clinical study
Data availability: GSE52490
Code availability: -