circRNA basic information
circBase ID: hsa_circ_0006677
Name: hsa_circ_WDR78
Synonym: circ_0006677
Host Gene: WDR78
Genomic location(hg19): chr1:67356836-67371058:-
Genomic location(hg38): chr1:66891153-66905375:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005494
MONDO name: triple-negative breast carcinoma
Disease details: triple-negative breast cancer / TNBC
Disease DO ID:
 0060081
Disease MeSH ID:
 D064726
Disease NCIt ID:
 C71732
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

adjacent frozen tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: EIF4A3
Associated microRNA: -
Biological function: Putatively participates in TNBC-related gene regulation via predicted RBP binding (in silico).
Molecular mechanism: Predicted circRNA-RBP interaction (CircInteractome/CLIP-seq-based).
Biological pathway or process:

not specified
Detected method:
S
Validation methods:

RNA-seq; Bioinformatics Analysis
Clinical significance:

-
Description:

hsa_circ_0006677 is down-regulated in TNBC in RNA-seq and was analyzed for predicted RBP interactions, implicating a possible role in gene regulatory processes.
Confidence score:

0.1768
Other information
Title:

Triple-Negative Breast Cancer circRNAome Reveals Hsa_circ_0072309 as a Potential Risk Biomarker.

Journal: Cancers
Published: 2022
PubMed ID: 35805051
Study type:

bioinformatics study
Data availability: PRJNA808398
Code availability: -