circRNA basic information
circBase ID: hsa_circ_0006948
Name: -
Synonym: -
Host Gene: -
Genomic location(hg19): chr3:171830241-171944737:+
Genomic location(hg38): chr3:172112451-172226947:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0002974
MONDO name: cervical cancer
Disease details: cervical cancer / CC
Disease DO ID:
 4362
Disease MeSH ID:
 -
Disease NCIt ID:
 C9311
Disease ICD11 ID:
 1256072522
Disease OMIM ID:
 603956
Species: Human
Species details: Homo sapiens
Tissue specimen:

CC tissues; paired-paracancerous cervical tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-217, hsa-miR-30b-3p, hsa-miR-136-5p, hsa-miR-185-3p, hsa-miR-501-5p, hsa-miR-658
Biological function: -
Molecular mechanism: ceRNA mechanism (circRNA-related miRNAs prognostic signature construction)
Biological pathway or process:

ceRNA regulation (other)
Detected method:
S
M
Validation methods:

Microarray; RNA-seq; Bioinformatics Analysis
Clinical significance:

Identified as a CC-specific differentially expressed circRNA used to derive a circRNA-related prognostic signature (via related miRNAs) for overall survival prediction.
Description:

hsa_circ_0006948 is up-regulated in cervical cancer tissues versus paired paracancerous cervical tissues based on GEO datasets and was used (together with two other circRNAs) to derive a circRNA-related miRNA prognostic signature via predicted circRNA-miRNA interactions.
Confidence score:

0.2465
Other information
Title:

Systematic analyses of a novel circRNA-related miRNAs prognostic signature for Cervical Cancer.

Journal: Genetics and molecular biology
Published: 2022
PubMed ID: 35766420
Study type:

bioinformatics study
Data availability: GSE102686; GSE107472; TCGA
Code availability: -