circRNA basic information
circBase ID: hsa_circ_0020093
Name: hsa_circ_ATRNL1
Synonym: -
Host Gene: ATRNL1
Genomic location(hg19): chr10:116879948-116889297:+
Genomic location(hg38): chr10:115120184-115129535:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0008487
MONDO name: polycystic ovary syndrome
Disease details: polycystic ovary syndrome
Disease DO ID:
 11612
Disease MeSH ID:
 D011085
Disease NCIt ID:
 C26862
Disease ICD11 ID:
 1213633323
Disease OMIM ID:
 184700
Species: Human
Species details: Homo sapiens
Tissue specimen:

granulosa cells
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: unknown
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
Q
S
Validation methods:

RNA-seq; Back-Splice Junction PCR / divergent primers PCR; Sanger Sequencing; RT-qPCR; Clinical Sample Validation
Clinical significance:

potential PCOS biomarkers
Description:

hsa_circ_0020093 is down-regulated in granulosa cells from women of reproductive age with PCOS versus controls, validated by qRT-PCR. The study did not define its downstream targets or mechanism in PCOS.
Confidence score:

0.5541
Other information
Title:

Circular RNA expression profiling of granulosa cells in women of reproductive age with polycystic ovary syndrome.

Journal: Archives of gynecology and obstetrics
Published: 2019
PubMed ID: 30937532
Study type:

combined biological and clinical study
Data availability: Electronic supplementary material (10.1007/s00404-019-05129-5)
Code availability: -