circRNA basic information
circBase ID: hsa_circ_0040705
Name: -
Synonym: -
Host Gene: -
Genomic location(hg19): chr16:84792321-84801964:+
Genomic location(hg38): chr16:84758715-84768358:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0007256
MONDO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma / HCC
Disease DO ID:
 684, 686
Disease MeSH ID:
 D006528
Disease NCIt ID:
 C3099
Disease ICD11 ID:
 1294035808
Disease OMIM ID:
 114550
Species: Human
Species details: Homo sapiens
Tissue specimen:

cancerous HCC tissues; paracancerous samples
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UN
Associated gene: EZH2
Associated microRNA: hsa-miR-527, hsa-miR-518a-5p
Biological function: -
Molecular mechanism: Predicted ceRNA competition for EZH2 via miRNAs
Biological pathway or process:

ceRNA regulation (other)
Detected method:
M
Validation methods:

Microarray; Bioinformatics Analysis
Clinical significance:

-
Description:

hsa_circ_0040705 was identified bioinformatically as a putative ceRNA competitor involved in EZH2-related axes (via hsa-miR-527 or hsa-miR-518a-5p) in HCC. No experimental validation, direction of dysregulation, or clinical prognostic association was reported for this circRNA.
Confidence score:

0.1768
Other information
Title:

Comprehensive competitive endogenous RNA network analysis reveals EZH2-related axes and prognostic biomarkers in hepatocellular carcinoma.

Journal: Iranian journal of basic medical sciences
Published: 2022
PubMed ID: 35656182
Study type:

bioinformatics study
Data availability: GSE94508; GSE97332; TCGA
Code availability: -