circRNA basic information
circBase ID: hsa_circ_0101996
Name: hsa_circ_SOS2
Synonym: circRNA_101996
Host Gene: SOS2
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0002974
MONDO name: cervical cancer
Disease details: cervical cancer / CC
Disease DO ID:
 4362
Disease MeSH ID:
 -
Disease NCIt ID:
 C9311
Disease ICD11 ID:
 1256072522
Disease OMIM ID:
 603956
Species: Human
Species details: Homo sapiens
Tissue specimen:

CC tissues; normal para-carcinoma samples
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UN
Associated gene: Ras-mediated signaling pathway
Associated microRNA: -
Biological function: unknown
Molecular mechanism: ceRNA sponge mechanism in a circRNA-miRNA-mRNA network
Biological pathway or process:

ceRNA regulation (other)
Detected method:
M
Validation methods:

Microarray; Bioinformatics Analysis
Clinical significance:

-
Description:

This study highlighted hsa_circ_0101996 (circRNA_101996) as a key circRNA within an inferred CC ceRNA network, acting as a putative miRNA sponge. It is derived from the host gene SOS2 and was prioritized due to an “up-down-up” circRNA-miRNA-mRNA expression pattern, suggesting a potentially important regulatory role worth further validation.
Confidence score:

0.1768
Other information
Title:

CircRNA-Based Cervical Cancer Prognosis Model, Immunological Validation and Drug Prediction.

Journal: Current oncology (Toronto, Ont.)
Published: 2022
PubMed ID: 36354693
Study type:

bioinformatics study
Data availability: GSE102686
Code availability: -