circRNA basic information
circBase ID: hsa_circ_0004788
Name: -
Synonym: -
Host Gene: -
Genomic location(hg19): chr3:78987750-78988077:-
Genomic location(hg38): chr3:78938600-78938927:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
0007256
MONDO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma / HCC
Disease DO ID:
684, 686
Disease MeSH ID:
D006528
Disease NCIt ID:
C3099
Disease ICD11 ID:
1294035808
Disease OMIM ID:
114550
Species: Human
Species details: Homo sapiens
Tissue specimen:

tumour tissue samples; paired adjacent normal tissue samples

Cell lines:

-

In vivo animal model:

-

circRNA-disease information
Expression pattern:
DS
Associated gene: -
Associated microRNA: -
Biological function: unknown
Molecular mechanism: ceRNA network prediction (circRNA-miRNA-mRNA network constructed), but no specific validated axis reported for this circRNA.
Biological pathway or process:

ceRNA regulation (other)

Detected method:
Q
M
Validation methods:

Microarray; RT-qPCR; Clinical Sample Validation; Bioinformatics Analysis

Clinical significance:

Part of five selected circRNAs used to build ceRNA networks; overall, the identified circRNA-miRNA-mRNA axes correlate negatively with HCC prognosis (not specified per hsa_circ_0004788).

Description:

hsa_circ_0004788 was one of five statistically significant circRNAs in HCC validated by qRT-PCR and included for downstream ceRNA network construction via database prediction. The paper did not report a specific circRNA-miRNA-mRNA prognostic axis for hsa_circ_0004788.

Confidence score:

0.4032

Other information
Title:

Construction of a ceRNA regulatory network to explore potential pathogenesis mechanisms involved in human hepatocellular carcinoma.

Journal: Scientific reports
Published: 2023
PubMed ID: 38086834
Study type:

combined biological and clinical study

Data availability: GSE242797
Code availability: -