circRNA basic information
circBase ID: -
Name: hsa_circ_ZNF532
Synonym: circRNA46229
Host Gene: ZNF532
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0002974
MONDO name: cervical cancer
Disease details: cervical cancer
Disease DO ID:
 4362
Disease MeSH ID:
 -
Disease NCIt ID:
 C9311
Disease ICD11 ID:
 1256072522
Disease OMIM ID:
 603956
Species: Human
Species details: Homo sapiens
Tissue specimen:

HPV negative normal cervical epithelium; HPV16 positive normal cervical epithelium; HPV16 positive high-grade squamous intraepithelial lesion; HPV16 positive cervical squamous epithelial cell carcinoma tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: RBM5, ELAVL1, ELAVL3, UPF1, TAF15, CPSF6, NUDT21, FUS, NOP58, U2AF2, HNRNPL, HNRNPA2B1, PTBP1, HNRNPC, ZNF184, MSI1, HNRNPA1, LIN28A, IGF2BP2, MBNL2, TARDBP, RBFOX2, TIAL1, AGO2, EIF4A3, FBL
Associated microRNA: -
Biological function: Potential RBP-associated circRNA mediating transcriptional, post-transcriptional, or translational regulation in cervical cancer progression.
Molecular mechanism: Predicted RBP interaction mechanism; no miRNA partner predicted.
Biological pathway or process:

other pathway/process (other)
Detected method:
S
Validation methods:

Bioinformatics Analysis; RNA-seq
Clinical significance:

Potential marker for cervical cancer progression.
Description:

circRNA46229/hsa-ZNF532_0016 was identified as a DE circRNA in cervical cancer progression. Unlike the other DE circRNAs, it had no predicted miRNA partner and was proposed to act through predicted RBP interactions that may affect transcriptional, post-transcriptional, or translational regulation.
Confidence score:

0.1768
Other information
Title:

Exploring the role of circRNA-miRNA-mRNA interactions in cervical cancer progression: insights into HPV status and potential therapeutic approaches.

Journal: Journal of applied genetics
Published: 2025
PubMed ID: 40531429
Study type:

bioinformatics study
Data availability: GSE147009; TCGA; CircAtlas; Transcirc; MiRWalk 3.0; CMAP2; CTDBASE
Code availability: -