circRNA basic information
circBase ID: -
Name: hsa_circ_ITCH
Synonym: -
Host Gene: ITCH
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0001056
MONDO name: gastric cancer
Disease details: gastric cancer
Disease DO ID:
 10534
Disease MeSH ID:
 -
Disease NCIt ID:
 C9331
Disease ICD11 ID:
 1397617262
Disease OMIM ID:
 613659
Species: Human
Species details: Homo sapiens
Tissue specimen:

gastric cancer tissues; matched adjacent nontumoral tissues
Cell lines:

A540
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: unknown
Molecular mechanism: not specified
Biological pathway or process:

not specified
Detected method:
Q
Validation methods:

divergent primers PCR; Sanger Sequencing; RT-qPCR; Clinical Sample Validation
Clinical significance:

cir_ITCH expression levels were related with numerous clinicopathological features of tumoral tissues; may serve in future as potential prognostic biomarkers in cancer
Description:

cir_ITCH is significantly down-regulated in gastric cancer tumoral tissues versus paired adjacent nontumoral tissues, and its expression is associated with clinicopathological features. The study suggests it may serve as a potential prognostic biomarker, but does not define a specific mechanism in GC.
Confidence score:

0.5129
Other information
Title:

Down-regulation of circular RNA ITCH and circHIPK3 in gastric cancer tissues.

Journal: Turkish journal of medical sciences
Published: 2019
PubMed ID: 30866608
Study type:

clinical study
Data availability: -
Code availability: -