circRNA basic information
circBase ID: -
Name: hsa_circ_ANRIL
Synonym: -
Host Gene: ANRIL
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0012727
MONDO name: Kawasaki disease
Disease details: Kawasaki disease
Disease DO ID:
 13378
Disease MeSH ID:
 D009080
Disease NCIt ID:
 C34825
Disease ICD11 ID:
 540285662
Disease OMIM ID:
 611775
Species: Human
Species details: Homo sapiens
Tissue specimen:

serum
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: Potential diagnostic biomarker for Kawasaki disease; may be related to IVIG therapy response.
Molecular mechanism: not specified
Biological pathway or process:

not specified
Detected method:
Q
Validation methods:

RT-qPCR; Clinical Sample Validation; ROC Analysis
Clinical significance:

Serum circANRIL shows diagnostic value for KD (AUC 0.624).
Description:

Serum circANRIL is decreased in acute Kawasaki disease compared with healthy controls and increases after IVIG therapy. It shows modest diagnostic performance and is proposed as a potential early diagnostic biomarker for KD.
Confidence score:

0.4187
Other information
Title:

Aberrant expression of serum circANRIL and hsa_circ_0123996 in children with Kawasaki disease.

Journal: Journal of clinical laboratory analysis
Published: 2019
PubMed ID: 30843267
Study type:

clinical study
Data availability: -
Code availability: -