circRNA basic information
circBase ID: hsa_circ_0003570
Name: -
Synonym: -
Host Gene: -
Genomic location(hg19): chr10:126370175-126384781:-
Genomic location(hg38): chr10:124681606-124696212:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0007256
MONDO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma / HCC
Disease DO ID:
 684, 686
Disease MeSH ID:
 D006528
Disease NCIt ID:
 C3099
Disease ICD11 ID:
 1294035808
Disease OMIM ID:
 114550
Species: Human
Species details: Homo sapiens
Tissue specimen:

tumor tissue; adjacent nontumor tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: Potential tumor suppressor role (hypothesized).
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
Q
Validation methods:

RT-qPCR; Clinical Sample Validation; Cohort Study; Survival Analysis
Clinical significance:

High hsa_circ_0003570 expression was an independent prognostic factor for overall survival and progression-free survival in HCC patients.
Description:

In HCC clinical tissues, hsa_circ_0003570 is down-regulated in tumors versus adjacent noncancerous liver tissue. Higher expression predicts better overall and progression-free survival, supporting its potential as a prognostic biomarker; no mechanism was experimentally investigated in this study.
Confidence score:

0.4758
Other information
Title:

Circular Noncoding RNA hsa_circ_0003570 as a Prognostic Biomarker for Hepatocellular Carcinoma.

Journal: Genes
Published: 2022
PubMed ID: 36011395
Study type:

clinical study
Data availability: The datasets used or analyzed during the current study are available from the corresponding author on reasonable request.
Code availability: -