circRNA basic information
circBase ID: -
Name: hsa_circ_MISP
Synonym: circMISP
Host Gene: MISP
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0001056
MONDO name: gastric cancer
Disease details: Gastric cancer / GC
Disease DO ID:
 10534
Disease MeSH ID:
 -
Disease NCIt ID:
 C9331
Disease ICD11 ID:
 1397617262
Disease OMIM ID:
 613659
Species: Human
Species details: Homo sapiens
Tissue specimen:

gastric cancer tissue; adjacent normal tissues / non-neoplastic gastric tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: MISP
Associated microRNA: hsa-miR-508-5p, hsa-miR-873-5p, hsa-miR-125a-5p, hsa-miR-1236-3p, hsa-miR-138-5p, hsa-miR-148b-3p, hsa-miR-148a-3p, hsa-miR-151a-5p, hsa-miR-152-5p, hsa-miR-193a-5p, hsa-miR-193a-3p, hsa-miR-199a-5p, hsa-miR-204-5p, hsa-miR-24-3p, hsa-miR-28-5p, hsa-miR-296-5p, hsa-miR-29a-3p, hsa-miR-302b-3p, hsa-miR-326, hsa-miR-331-3p, hsa-miR-338-3p, hsa-miR-346, hsa-miR-375, hsa-miR-423-5p, hsa-miR-486-5p, hsa-miR-491-5p
Biological function: Not specified
Molecular mechanism: Predicted circRNA-miRNA interactions (computational).
Biological pathway or process:

ceRNA regulation (other)
Detected method:
Q
S
Validation methods:

RNA-seq; Bioinformatics Analysis; RT-qPCR; divergent primers PCR; Clinical Sample Validation
Clinical significance:

-
Description:

circMISP is up-regulated in gastric cancer tissues versus adjacent normal tissues and its expression change was validated by RT-qPCR. Its interactions with multiple miRNAs were predicted by miRanda-based bioinformatic analysis.
Confidence score:

0.5135
Other information
Title:

Identification of circRNA Biomarker for Gastric Cancer through Integrated Analysis.

Journal: Frontiers in molecular biosciences
Published: 2022
PubMed ID: 35359600
Study type:

combined biological and clinical study
Data availability: China National Center for Bioinformation, accession PRJCA008130
Code availability: -