circRNA basic information
circBase ID: -
Name: hsa_circ_ZNF827
Synonym: hsa_circRNA_403236 / hsa-circRNA-403236
Host Gene: ZNF827
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
0007254
MONDO name: breast cancer
Disease details: breast cancer
Disease DO ID:
1612
Disease MeSH ID:
-
Disease NCIt ID:
C9335
Disease ICD11 ID:
1047754165
Disease OMIM ID:
-
Species: Human
Species details: Homo sapiens
Tissue specimen:

breast cancer tissues; adjacent non-tumor breast tissues; matched-normal tissues

Cell lines:

-

In vivo animal model:

-

circRNA-disease information
Expression pattern:
UP
Associated gene: collagens family of proteins
Associated microRNA: hsa-miR-29a-3p
Biological function: -
Molecular mechanism: Predicted ceRNA interaction (circRNA binds miRNA that targets collagen-related genes).
Biological pathway or process:

ceRNA regulation (other); other pathway/process (other)

Detected method:
M
Validation methods:

Microarray; Bioinformatics Analysis

Clinical significance:

-

Description:

hsa_circRNA_403236 is up-regulated in breast cancer and is predicted to bind miR-29a-3p, potentially influencing extracellular matrix/cell communication programs via miR-29a-3p target genes (e.g., collagens).

Confidence score:

0.1768

Other information
Title:

Circular RNA mediated gene regulation in human breast cancer: A bioinformatics analysis.

Journal: PloS one
Published: 2023
PubMed ID: 37494404
Study type:

bioinformatics study

Data availability: GSE182471; TCGA (February 2022, breast invasive carcinoma (brca))
Code availability: -