circRNA basic information
circBase ID: -
Name: hsa_circ_FOXO3
Synonym: -
Host Gene: FOXO3
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0018177
MONDO name: glioblastoma
Disease details: glioblastoma
Disease DO ID:
 3068
Disease MeSH ID:
 D005909
Disease NCIt ID:
 C3058
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

plasma
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: Potential circulating biomarker/fingerprint for predicting the occurrence of GBM.
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
Q
Validation methods:

RT-qPCR; RNase R Treatment; ROC Analysis; Bioinformatics Analysis; Clinical Sample Validation
Clinical significance:

May serve as a plasma fingerprint/marker for predicting the occurrence of GBM; used in a diagnostic risk score model with ROC AUC reported.
Description:

circFOXO3 is up-regulated in GBM patient plasma and was selected in the validation set as a potential circulating fingerprint for predicting GBM occurrence, contributing to a multi-circRNA diagnostic risk score with high AUC.
Confidence score:

0.559
Other information
Title:

Plasmatic circRNA Predicting the Occurrence of Human Glioblastoma.

Journal: Cancer management and research
Published: 2020
PubMed ID: 32425605
Study type:

combined biological and clinical study
Data availability: -
Code availability: -