circRNA basic information
circBase ID: hsa_circ_0008336
Name: hsa_circ_BBS9
Synonym: -
Host Gene: BBS9
Genomic location(hg19): chr7:33397466-33427756:+
Genomic location(hg38): chr7:33357854-33388144:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0009807
MONDO name: osteosarcoma
Disease details: osteosarcoma / OS
Disease DO ID:
 3347
Disease MeSH ID:
 D012516
Disease NCIt ID:
 C9145
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

-
Cell lines:

U2OS; U2OS-R; MG63; MG63-R
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: May be involved in cisplatin resistance in osteosarcoma cells.
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
Q
S
Validation methods:

RNA-seq; RT-qPCR; Back-Splice Junction PCR / divergent primers PCR
Clinical significance:

-
Description:

hsa_circ_0008336 is up-regulated in cisplatin-resistant osteosarcoma cell lines (U2OS-R and MG63-R) compared with their parental cells, suggesting a potential association with cisplatin resistance. No specific downstream mechanism was experimentally defined in this study.
Confidence score:

0.3401
Other information
Title:

Circular RNA expression pattern in cisplatin-resistant osteosarcoma cells.

Journal: Translational cancer research
Published: 2020
PubMed ID: 35117180
Study type:

biological research
Data availability: -
Code availability: -