| Expression pattern: |
DN |
| Associated gene: |
- |
| Associated microRNA: |
- |
| Biological function: |
Potential diagnostic biomarker for HCC; no functional assays specific to circMERTK were reported. |
| Molecular mechanism: |
Potential circRNA-miRNA-mRNA network predicted by bioinformatics; no specific validated mechanism was reported. |
| Biological pathway or process: |
ceRNA regulation (other); other pathway/process (other) |
| Detected method: |
Q
S
|
| Validation methods: |
Back-Splice Junction PCR / divergent primers PCR; RNase R Treatment; Sanger Sequencing; RT-qPCR; RNA-seq; Clinical Sample Validation; ROC Analysis; Bioinformatics Analysis |
| Clinical significance: |
Good performance in discriminating HCC tissues from normal tissues; AUC = 0.783. |
| Description: |
circMERTK was significantly downregulated in HCC tissues and showed diagnostic value for distinguishing HCC from adjacent normal tissues. The study did not report circMERTK-specific functional experiments or validated molecular mechanisms. |
| Confidence score: |
0.6841 |