circRNA basic information
circBase ID: hsa_circ_0028502
Name: hsa_circ_SLC24A6
Synonym: -
Host Gene: SLC24A6
Genomic location(hg19): chr12:113753139-113754806:-
Genomic location(hg38): chr12:113315334-113317001:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0007256
MONDO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Disease DO ID:
 684, 686
Disease MeSH ID:
 D006528
Disease NCIt ID:
 C3099
Disease ICD11 ID:
 1294035808
Disease OMIM ID:
 114550
Species: Human
Species details: Homo sapiens
Tissue specimen:

HCC tissue; adjacent nontumorous liver tissue; liver tissue
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: unknown
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
Q
M
Validation methods:

Microarray; RT-qPCR; Back-Splice Junction PCR / divergent primers PCR; Sanger Sequencing; Clinical Sample Validation; ROC Analysis; Cohort Study; Survival Analysis
Clinical significance:

Potential diagnostic biomarker for HCC; distinguishes HCC from LC and CH, and LC from CH (ROC analysis).
Description:

hsa_circ_0028502 is significantly down-regulated in HCC tissues and shows progressively decreased expression from CH to LC to HCC. It has diagnostic value for distinguishing HCC from LC/CH and LC from CH based on ROC analysis.
Confidence score:

0.6813
Other information
Title:

Hsa_circ_0028502 and hsa_circ_0076251 are potential novel biomarkers for hepatocellular carcinoma.

Journal: Cancer medicine
Published: 2019
PubMed ID: 31595711
Study type:

combined biological and clinical study
Data availability: GSE94508
Code availability: -