| Expression pattern: |
UP |
| Associated gene: |
FNDC1, HTRA1, IER5 L, IFIT2, NDUFA4L2, SERPINE1 |
| Associated microRNA: |
hsa-miR-765, hsa-miR-198, hsa-miR-125a-3 p, hsa-miR-486-5 p |
| Biological function: |
Associated with gastric cancer progression and prognosis as a component of the ceRNA prognostic subnetwork. |
| Molecular mechanism: |
Predicted ceRNA mechanism in a circRNA-miRNA-mRNA regulatory subnetwork. |
| Biological pathway or process: |
ceRNA regulation (other); PI3K/AKT (other); p53 signaling (other); HIF-1 signaling (other); proliferation (promotes); migration (promotes); invasion (promotes) |
| Detected method: |
Q
M
|
| Validation methods: |
Microarray; RT-qPCR; Clinical Sample Validation; Bioinformatics Analysis; Survival Analysis |
| Clinical significance: |
Potential prognostic biomarker in gastric cancer. |
| Description: |
hsa_circ_0007094 was identified as an up-regulated circRNA in gastric cancer and validated by RT-qPCR in clinical tissues. It was included in a predicted circRNA-miRNA-mRNA prognostic ceRNA subnetwork associated with GC progression and prognosis. |
| Confidence score: |
0.5047 |