circRNA basic information
circBase ID: -
Name: hsa_circ_EMB
Synonym: circEMB
Host Gene: EMB
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0004844
MONDO name: oral mucosa leukoplakia
Disease details: oral leukoplakia
Disease DO ID:
 9655
Disease MeSH ID:
 D007972
Disease NCIt ID:
 C3187
Disease ICD11 ID:
 417308277
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

OLK tissue; normal oral mucosal (NOM) tissue
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
Q
S
Validation methods:

RNA-seq; RT-qPCR; Back-Splice Junction PCR / divergent primers PCR; Clinical Sample Validation
Clinical significance:

-
Description:

circEMB is significantly down-regulated in OLK compared with NOM and validated by RT-qPCR consistent with RNA-seq. No additional mechanism or clinical significance is provided for circEMB in this paper.
Confidence score:

0.4773
Other information
Title:

Comprehensive analysis of circular RNA in oral leukoplakia: upregulated circHLA-C as a potential biomarker for diagnosis and prognosis.

Journal: Annals of translational medicine
Published: 2020
PubMed ID: 33313120
Study type:

combined biological and clinical study
Data availability: GSE131568
Code availability: -