circRNA basic information
circBase ID: -
Name: hsa_circ_CCNB1
Synonym: circCCNB1_7_6
Host Gene: CCNB1
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: cytoplasm
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005575
MONDO name: colorectal cancer
Disease details: colorectal cancer
Disease DO ID:
 5672, 9256
Disease MeSH ID:
 -
Disease NCIt ID:
 C4978
Disease ICD11 ID:
 -
Disease OMIM ID:
 114500
Species: Human
Species details: Homo sapiens
Tissue specimen:

tumor tissue; adjacent non-tumor tissues
Cell lines:

HCT116; HT-29
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: unknown
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
Q
Validation methods:

Back-Splice Junction PCR / divergent primers PCR; RNase R Treatment; Sanger Sequencing; RT-qPCR; Clinical Sample Validation
Clinical significance:

-
Description:

circCCNB1_7_6 is significantly up-regulated in colorectal cancer tumor tissues versus paired adjacent non-tumor tissues, and was part of a panel of selected circRNAs validated as bona fide circRNAs. No downstream function or mechanism for circCCNB1_7_6 was further investigated in this study.
Confidence score:

0.5531
Other information
Title:

Noncoding Effects of Circular RNA CCDC66 Promote Colon Cancer Growth and Metastasis.

Journal: Cancer research
Published: 2017
PubMed ID: 28249903
Study type:

combined biological and clinical study
Data availability: -
Code availability: -