circRNA basic information
circBase ID: -
Name: hsa_circ_BRIP1
Synonym: circBRIP
Host Gene: BRIP1
Genomic location(hg19): chr17:59853761-59861785:.
Genomic location(hg38): chr17:61776400-61784424:.
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0007254
MONDO name: breast cancer
Disease details: breast cancer
Disease DO ID:
 1612
Disease MeSH ID:
 -
Disease NCIt ID:
 C9335
Disease ICD11 ID:
 1047754165
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

-
Cell lines:

MCF-7; MDA-MB-231
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
Q
S
Validation methods:

RNA-seq; RT-qPCR; divergent primers PCR; RNase R Treatment
Clinical significance:

-
Description:

circBRIP is among six circRNAs validated by RT-qPCR and is down-regulated in mammosphere-derived BCSCs versus adherent non-BCSCs. No specific functional mechanism for circBRIP was experimentally characterized beyond expression profiling.
Confidence score:

0.437
Other information
Title:

Circular RNA profile indicates circular RNA VRK1 is negatively related with breast cancer stem cells.

Journal: Oncotarget
Published: 2017
PubMed ID: 29221160
Study type:

combined biological and bioinformatics study
Data availability: -
Code availability: -