circRNA basic information
circBase ID: hsa_circ_0001897
Name: -
Synonym: -
Host Gene: -
Genomic location(hg19): chr9:134381500-134381840:+
Genomic location(hg38): chr9:131506113-131506453:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
0001056
MONDO name: gastric cancer
Disease details: gastric cancer / GC
Disease DO ID:
10534
Disease MeSH ID:
-
Disease NCIt ID:
C9331
Disease ICD11 ID:
1397617262
Disease OMIM ID:
613659
Species: Human
Species details: Homo sapiens
Tissue specimen:

-

Cell lines:

MGC-803; SGC-7901; NCI-N87; GES-1

In vivo animal model:

-

circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-150-5p, hsa-miR-29a-3p, hsa-miR-29c-3p, hsa-miR-29b-3p, hsa-miR-767-5p
Biological function: May inhibit invasion and metastasis of gastric cancer cells.
Molecular mechanism: Predicted ceRNA-like interaction with miR-150-5p.
Biological pathway or process:

invasion (inhibits); metastasis (inhibits); ceRNA regulation (other)

Detected method:
M
Validation methods:

RNase R Treatment; Microarray; Bioinformatics Analysis

Clinical significance:

Reported by literature retrieval to be related to gastric cancer staging and metastasis.

Description:

hsa_circ_0001897 was down-regulated in gastric cancer cell lines compared with normal gastric epithelial cells based on circRNA microarray data. The authors predicted that it may interact with miR-150-5p and may suppress gastric cancer cell invasion and metastasis.

Confidence score:

0.329

Other information
Title:

[Differentially expressed circular RNAs in human gastric cancer cells].

Journal: Sheng li xue bao : [Acta physiologica Sinica]
Published: 2018
PubMed ID: 30112563
Study type:

combined biological and bioinformatics study

Data availability: -
Code availability: -