circRNA basic information
circBase ID: hsa_circ_0100609
Name: -
Synonym: -
Host Gene: -
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0007256
MONDO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma / HCC
Disease DO ID:
 684, 686
Disease MeSH ID:
 D006528
Disease NCIt ID:
 C3099
Disease ICD11 ID:
 1294035808
Disease OMIM ID:
 114550
Species: Human
Species details: Homo sapiens
Tissue specimen:

HCC tissues; adjacent non-cancerous tissues / paracancerous tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DS
Associated gene: PLOD2, TARS, RNF19B, CCT2, RAN, C5orf30, MCM10
Associated microRNA: -
Biological function: May play key roles in the progression/development of HCC.
Molecular mechanism: circRNA-associated ceRNA network (predicted).
Biological pathway or process:

ceRNA regulation (other)
Detected method:
Q
S
M
Validation methods:

Microarray; RNA-seq; RT-qPCR; Clinical Sample Validation; Bioinformatics Analysis
Clinical significance:

Identified as a key hub circRNA in the HCC ceRNA network and proposed as a prognostic biomarker.
Description:

hsa_circ_0100609 was identified as a hub circRNA in an HCC ceRNA network and was validated as differentially expressed in HCC tumors versus paracancerous tissues, supporting its potential relevance to HCC progression and prognosis modeling.
Confidence score:

0.4297
Other information
Title:

Detection of Prognostic Biomarkers for Hepatocellular Carcinoma through CircRNA-associated CeRNA Analysis.

Journal: Journal of clinical and translational hepatology
Published: 2022
PubMed ID: 35233376
Study type:

combined biological and clinical study
Data availability: GSE125469; TCGA
Code availability: -