| Expression pattern: |
UN |
| Associated gene: |
- |
| Associated microRNA: |
hsa-miR-608 |
| Biological function: |
Identified as a differentially expressed circRNA and potential key player in cervical cancer; it interacted with hsa-miR-608 and may influence pathological processes of cervical cancer. |
| Molecular mechanism: |
Potential circRNA-miRNA regulatory mechanism involving hsa_circ_0007766 and hsa-miR-608 in the HIF-1 signaling pathway context, with host gene ERBB2. |
| Biological pathway or process: |
HIF-1 signaling (other); ceRNA regulation (other) |
| Detected method: |
Q
S
|
| Validation methods: |
RNA-seq; RT-qPCR; Sanger Sequencing; Bioinformatics Analysis |
| Clinical significance: |
Potential key player in cervical cancer; interaction with hsa-miR-608 may influence the pathological process of cervical cancer. |
| Description: |
hsa_circ_0007766 was identified as a validated CXCR2 deficiency-associated differentially expressed circRNA in HeLa cells. It is linked to HIF-1 signaling through its host gene ERBB2 and was predicted to interact with hsa-miR-608, suggesting a potential role in cervical cancer pathology. |
| Confidence score: |
0.3858 |