circRNA basic information
circBase ID: hsa_circ_0000518
Name: -
Synonym: -
Host Gene: -
Genomic location(hg19): chr14:20811404-20811554:-
Genomic location(hg38): chr14:20343245-20343395:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005061
MONDO name: lung adenocarcinoma
Disease details: lung adenocarcinoma
Disease DO ID:
 3910
Disease MeSH ID:
 C538231
Disease NCIt ID:
 C3512
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

LUAD tissues; adjacent non-tumor tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: hsa_circ_0000518 was significantly overexpressed in LUAD samples, but the study did not further characterize its biological function.
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
Q
M
Validation methods:

Microarray; RT-qPCR; Clinical Sample Validation; Bioinformatics Analysis
Clinical significance:

-
Description:

hsa_circ_0000518 was evaluated as a candidate circRNA in LUAD tissues and was found to be significantly overexpressed in LUAD samples. The paper did not report further mechanistic, functional, or prognostic validation for this circRNA.
Confidence score:

0.4032
Other information
Title:

Transcription factor MAFK binds to circRPPH to regulate SIRT gene-mediated cellular pyroptosis and lung adenocarcinoma progression.

Journal: International immunopharmacology
Published: 2025
PubMed ID: 39602957
Study type:

combined biological and clinical study
Data availability: GSE158695; data available upon reasonable request
Code availability: -