circRNA basic information
circBase ID: hsa_circ_0027493
Name: -
Synonym: -
Host Gene: -
Genomic location(hg19): chr12:69218142-69218431:+
Genomic location(hg38): chr12:68824362-68824651:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0009807
MONDO name: osteosarcoma
Disease details: osteosarcoma
Disease DO ID:
 3347
Disease MeSH ID:
 D012516
Disease NCIt ID:
 C9145
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

human OS tissues; adjacent normal tissues
Cell lines:

human OS cells; human osteoblasts
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: Identified as a down-regulated DEcircRNA in OS and included in a constructed circRNA/miRNA/mRNA ceRNA network.
Molecular mechanism: Predicted ceRNA network involvement; no specific experimentally validated axis was reported for this circRNA in OS.
Biological pathway or process:

ceRNA regulation (other)
Detected method:
M
Validation methods:

Microarray; Bioinformatics Analysis
Clinical significance:

-
Description:

hsa_circ_0027493 was identified from public microarray datasets as a down-regulated circRNA in osteosarcoma. It was included in the predicted OS circRNA/miRNA/mRNA ceRNA network, but no circRNA-specific experimental validation or clinical survival analysis was reported for it.
Confidence score:

0.1768
Other information
Title:

The functions and clinical implications of hsa_circ_0032462-miR-488-3p-SLC7A1 axis in human osteosarcoma.

Journal: Bone
Published: 2025
PubMed ID: 39566705
Study type:

bioinformatics study
Data availability: GSE225588; GSE96964; https://doi.org/10.1016/j.bone.2024.117333
Code availability: -