circRNA basic information
circBase ID: hsa_circ_0000518
Name: hsa_circ_RPPH1
Synonym: -
Host Gene: RPPH1
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005575
MONDO name: colorectal cancer
Disease details: colorectal cancer / CRC
Disease DO ID:
 5672, 9256
Disease MeSH ID:
 -
Disease NCIt ID:
 C4978
Disease ICD11 ID:
 -
Disease OMIM ID:
 114500
Species: Human
Species details: Homo sapiens
Tissue specimen:

CRC tissues; corresponding normal tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: unknown
Biological function: Potential diagnostic marker in CRC (bioinformatics-identified DEcircRNA).
Molecular mechanism: not specified
Biological pathway or process:

not specified
Detected method:
M
Validation methods:

Microarray; Bioinformatics Analysis
Clinical significance:

Potential circRNA diagnostic marker for CRC.
Description:

HAS-circ-0000518 (host gene RPPH1) is predicted by GEO dataset mining to be up-regulated in CRC and is suggested as a potential diagnostic circRNA; no direct mechanistic axis is experimentally validated for this circRNA in the paper.
Confidence score:

0.1768
Other information
Title:

Bioinformatics analysis-based screening of circRNA gene with mainstream expression trend in colorectal cancer and construction of a coexpression regulatory network.

Journal: PloS one
Published: 2023
PubMed ID: 38064496
Study type:

bioinformatics study
Data availability: GSE126094; GSE21815; TCGA
Code availability: -