circRNA basic information
circBase ID: hsa_circ_0001446
Name: -
Synonym: circ_0001446
Host Gene: -
Genomic location(hg19): chr4:144530863-144566308:+
Genomic location(hg38): chr4:143609710-143645155:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0002974
MONDO name: cervical cancer
Disease details: cervical cancer
Disease DO ID:
 4362
Disease MeSH ID:
 -
Disease NCIt ID:
 C9311
Disease ICD11 ID:
 1256072522
Disease OMIM ID:
 603956
Species: Human
Species details: Homo sapiens
Tissue specimen:

cervical squamous cell carcinoma tissues; paired-paracancerous cervical tissues
Cell lines:

HcerEpic
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: Down-regulated circRNA included in the cervical cancer circRNA-miRNA-mRNA network construction; not individually functionally validated.
Molecular mechanism: Predicted participation in a circRNA-miRNA-mRNA ceRNA network.
Biological pathway or process:

ceRNA regulation (other)
Detected method:
M
Validation methods:

Microarray; Bioinformatics Analysis
Clinical significance:

-
Description:

circ_0001446 was a down-regulated circRNA with a consistent expression trend in the two cervical cancer GEO datasets. It was included in the predicted circRNA-miRNA-mRNA network, but no individual RT-qPCR or functional validation was reported.
Confidence score:

0.1768
Other information
Title:

Identification of circRNA-mediated competing endogenous RNA network involved in the development of cervical cancer.

Journal: Molecular and cellular probes
Published: 2024
PubMed ID: 39307294
Study type:

bioinformatics study
Data availability: GSE102686; GSE113696; TCGA-CESC
Code availability: -