circRNA basic information
circBase ID: hsa_circ_0084003
Name: hsa_circ_FGFR1
Synonym: circ_0084003
Host Gene: hsa-miR-143-3p
 
 
 
Disease basic information
DO ID:
 3498
DO name: pancreatic ductal adenocarcinoma
Disease details: pancreatic ductal adenocarcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: DNMT3A
Associated microRNA: hsa-miR-143-3p
Biological function: Hsa_circ_0084003 knockdown could notably inhibit the aerobic glycolysis and epithelial-mesenchymal transition of pancreatic ductal adenocarcinoma cells
Molecular mechanism: circ_0084003/hsa-miR-143-3p/DNMT3A axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

Therefore, hsa_circ_0084003 could be studied as a possible therapeutic target regarding pancreatic ductal adenocarcinoma.
Other information
Title:

Hsa_circ_0084003 modulates glycolysis and epithelial-mesenchymal transition in pancreatic ductal adenocarcinoma through targeting hsa-miR-143-3p/DNMT3A axis.

Journal: Toxicol Res (Camb)
Published: 2023/7/3
PubMed ID: 37397922