circRNA basic information
circBase ID: hsa_circ_0023404
Name: hsa_circ_CER
Synonym: circRNA_100876
Host Gene: hsa-miR-136, hsa-miR-217, hsa-miR-636, hsa-miR-646, hsa-miR-665
 
 
 
Disease basic information
DO ID:
 8398
DO name: osteoarthritis
Disease details: osteoarthritis
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: MMP13
Associated microRNA: hsa-miR-136, hsa-miR-217, hsa-miR-636, hsa-miR-646, hsa-miR-665
Biological function: promotes human cartilage degradation
Molecular mechanism: promoting MMP13 Expression by Functioning as a hsa-miR-136 Sponge
Survival: -
Supported No.:
 1
Description:

We demonstrated that circRNA-CER regulated MMP13 expression and participated in the process of chondrocyte ECM degradation.
Other information
Title:

Circular RNA Related to the Chondrocyte ECM Regulates MMP13 Expression by Functioning as a MiR-136 Sponge in Human Cartilage Degradation.

Journal: Sci Rep
Published: 2016/3/5
PubMed ID: 26931159