circRNA basic information
circBase ID: hsa_circ_0012634
Name: hsa_circ_TMEM59
Synonym: hsa_circRNA_100236
Host Gene: TMEM59
Genomic location(hg19): chr1:54506428-54509198:-
Genomic location(hg38): chr1:54040755-54043525:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005277
MONDO name: migraine disorder
Disease details: Migraine
Disease DO ID:
 6364
Disease MeSH ID:
 D008881
Disease NCIt ID:
 C89715
Disease ICD11 ID:
 669367341
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

plasma; peripheral blood
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: Hsa-miR-508-5p, Hsa-miR-372-5p, Hsa-miR-655-5p, Hsa-miR-519d-5p, Hsa-miR-668-3p
Biological function: unknown
Molecular mechanism: not specified
Biological pathway or process:

not specified
Detected method:
Q
M
Validation methods:

Microarray; RT-qPCR; RNase R Treatment; Clinical Sample Validation
Clinical significance:

-
Description:

hsa_circRNA_100236 (hsa_circ_0012634) is down-regulated in migraine patient plasma and validated by qRT-PCR. The study does not report a specific mechanism, pathway, or downstream targets for this circRNA beyond differential expression.
Confidence score:

0.4773
Other information
Title:

Differential Expression and Bioinformatic Analysis of the circRNA Expression in Migraine Patients.

Journal: BioMed research international
Published: 2020
PubMed ID: 33178826
Study type:

combined biological and clinical study
Data availability: All data generated or analyzed during this study are included in this article.
Code availability: -