circRNA basic information
circBase ID: -
Name: hsa_circ_FOXP1
Synonym: circFOXP1
Host Gene: FOXP1
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0850156
MONDO name: B-lymphoblastic leukemia/lymphoma MLL rearranged
Disease details: KMT2A rearranged AML
Disease DO ID:
 0080644
Disease MeSH ID:
 -
Disease NCIt ID:
 -
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

diagnosis pediatric AMLs
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UN
Associated gene: -
Associated microRNA: -
Biological function: Higher expression was significantly correlated with event-free survival in KMT2A rearranged AMLs.
Molecular mechanism: Not elucidated in this study.
Biological pathway or process:

not specified
Detected method:
S
Validation methods:

RNA-seq; Survival Analysis; Bioinformatics Analysis
Clinical significance:

Higher circFOXP1 expression was significantly correlated with EFS in KMT2A rearranged AMLs.
Description:

circFOXP1 was identified as a subgroup-specific prognostic circRNA in KMT2A rearranged AMLs. Its higher expression correlated with event-free survival, but the study did not elucidate its biological mechanism.
Confidence score:

0.348
Other information
Title:

circRNAs as prognostic markers in pediatric acute myeloid leukemia.

Journal: Cancer letters
Published: 2024
PubMed ID: 38621457
Study type:

bioinformatics study; clinical study
Data availability: HRA000789
Code availability: -