circRNA basic information
circBase ID: -
Name: hsa_circ_FNDC3B
Synonym: FNDC3B
Host Gene: FNDC3B
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0001056
MONDO name: gastric cancer
Disease details: gastric cancer
Disease DO ID:
 10534
Disease MeSH ID:
 -
Disease NCIt ID:
 C9331
Disease ICD11 ID:
 1397617262
Disease OMIM ID:
 613659
Species: Human
Species details: Homo sapiens
Tissue specimen:

human gastric cancer tissues; corresponding non-tumorous adjacent tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: Potentially related to gastric cancer metabolism and carcinometabolic enzyme activity; no direct functional experiment was performed for this circRNA.
Molecular mechanism: Predicted association with metabolic regulation and carcinometabolic enzyme activity based on whole-transcriptome sequencing and bioinformatics analysis.
Biological pathway or process:

other pathway/process (other)
Detected method:
Q
S
Validation methods:

RNA-seq; RT-qPCR; Clinical Sample Validation; Bioinformatics Analysis
Clinical significance:

-
Description:

FNDC3B/circFNDC3B was identified as a down-regulated key circRNA in gastric cancer tissues and validated by qRT-PCR. It is generated from the FNDC3B gene, and the study suggests key circRNAs may be linked to metabolic regulation and carcinometabolic enzyme activity in gastric cancer.
Confidence score:

0.4032
Other information
Title:

Identification of miRNA, lncRNA and circRNA associated with gastric cancer metabolism through sequencing and bioinformatics analysis.

Journal: Pathology, research and practice
Published: 2024
PubMed ID: 38290402
Study type:

combined bioinformatics and clinical study
Data availability: GSE224056
Code availability: -